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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1A
All Species:
41.21
Human Site:
Y207
Identified Species:
64.76
UniProt:
P10644
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10644
NP_002725.1
381
42982
Y207
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Chimpanzee
Pan troglodytes
XP_511647
260
29299
R115
E
D
A
A
S
Y
V
R
K
V
I
P
K
D
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537577
381
43019
Y207
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBC7
381
43167
Y207
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Rat
Rattus norvegicus
P09456
381
43076
Y207
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
Y452
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Chicken
Gallus gallus
Q5ZM91
382
43332
Y208
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Frog
Xenopus laevis
NP_001085084
381
43157
Y207
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Zebra Danio
Brachydanio rerio
NP_001017732
379
43009
Y205
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
Y202
F
G
E
L
A
L
I
Y
G
T
P
R
A
A
T
Honey Bee
Apis mellifera
XP_396167
372
41646
W215
A
K
T
D
V
K
L
W
G
I
D
R
D
S
Y
Nematode Worm
Caenorhab. elegans
P30625
366
41449
T204
A
A
T
V
I
A
K
T
D
V
K
L
W
A
I
Sea Urchin
Strong. purpuratus
Q26619
369
41770
R212
G
I
L
W
A
L
D
R
V
S
F
R
R
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
Y254
F
G
E
L
A
L
M
Y
N
S
P
R
A
A
T
Red Bread Mold
Neurospora crassa
Q01386
385
42138
N213
G
E
L
A
L
M
Y
N
A
P
R
A
A
T
V
Conservation
Percent
Protein Identity:
100
68.2
N.A.
97.9
N.A.
96.8
97.3
N.A.
58.7
92.4
92.6
91.5
N.A.
71.3
74
57.7
39.3
Protein Similarity:
100
68.2
N.A.
98.1
N.A.
97.3
98.4
N.A.
60
96
95.8
95.8
N.A.
81.6
85.3
73.4
56.9
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
13.3
6.6
20
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
34
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
14
74
7
0
0
7
0
0
7
74
74
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
7
0
7
0
7
0
7
7
0
% D
% Glu:
7
7
67
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
67
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
14
67
0
0
0
0
0
0
67
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
60
0
0
7
7
0
0
7
7
% I
% Lys:
0
7
0
0
0
7
7
0
7
0
7
0
7
0
0
% K
% Leu:
0
0
14
67
7
74
7
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
67
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
14
0
0
7
80
7
0
0
% R
% Ser:
0
0
0
0
7
0
0
0
0
14
0
0
0
7
0
% S
% Thr:
0
0
14
0
0
0
0
7
0
60
0
0
0
7
67
% T
% Val:
0
0
0
7
7
0
7
0
7
14
0
0
0
0
14
% V
% Trp:
0
0
0
7
0
0
0
7
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
7
7
67
0
0
0
0
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _